June 2015
Volume 11, Issue 6

Articadent® DENTAL (articaine HCl and epinephrine) Injection

Effective, reliable, fast-acting, and versatile anesthetic

Clinicians seek reliable, efficient ways to deliver the best care for their patients with every product and technique used in their dental practice while also ensuring their workflow runs smoothly. With this in mind, accomplishing many of the procedures performed in a dental practice hinges on the ability to consistently and effectively achieve profound anesthesia.

Using an anesthetic that can reliably, consistently, and predictably cause profound anesthesia on the first try is extremely important.

The articaine molecule became available in the United States more than a decade ago. Articadent has typical onset duration of 1 to 9 minutes, and it is quickly becoming the local anesthetic of choice for many dentists.

Articadent® is the articaine from DENTSPLY, a leading manufacturer and distributor of dental and other consumable healthcare products. Articadent® is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental procedures. Articadent® is manufactured with terminal sterilization, which is the preferred sterilization technique over aseptic processing as per FDA guidelines.* In addition, syringes and needles for dental injections do not change when switching molecules, making the switch to Articadent® very easy for clinicians. For effective, reliable pain management, choose Articadent®, the fast-acting, versatile anesthetic backed by the legacy of the DENTSPLY brand.

*SEE FDA’S 2004 GUIDANCE: Guidance for Industry Sterile Drug Products Produced by Aseptic Processing — Current Good Manufacturing Practice. “It is a well-accepted principle that sterile drugs should be manufactured using aseptic processing only when terminal sterilization is not feasible.”


· Reliable anesthesia with a typical onset time of less than 10 minutes
· Typically lasts approximately 1 hour for infiltrations and up to 2 hours for blocks
· Terminally sterilized
· Plunger and cartridge are silicon coated, giving plunger smooth movement and precise control
· Free from natural rubber latex, leading to reduced allergic reactions

Online Resources

Full prescribing information for Articadent DENTAL (articaine HCl and epinephrine) Injection is available at www.dentsply.com/en-us.

Important Safety Information

Articadent® is contraindicated in patients who are hypersensitive to products containing sulfite. Common precautions include aspiration prior to injection to help avoid intravascular injection. Local anesthetic solutions like Articadent® that contain a vasoconstrictor should be used cautiously especially in patients with impaired cardiovascular function or vascular disease. The most common adverse reactions (incidence >2%) are headache and pain. Articadent® should not be used in patients with congenital or idiopathic methemoglobinemia or in patients who are receiving treatment with methemoglobinemia-inducing agents.

DENSTPLY Pharmaceutical | 800-225-2787 | dentsplypharma.com

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